Excerpts from the book "Plants of the Gods", by Richard Evans Schultes and Albert Hofmann - ISBN 0-89281-406-3.
"The Andean cultures had half a dozen species of Brugmansias, known as Borrachero, Campanilla, Floripondio, Huanto, Huacacachu, Maicoa, Toe', Tongo, etc. A close relative is Methysticodendron, Culebra Borrachero, a powerful hallucinogen used by the Kamsa' Indians of Colombia" ... "Desfontainia spinosa, a beautiful shrub 1-6 feet in height, has glossy dark green leaves, resembling those of Christmas holly, and tubular red flowers with a yellow tip. The berry is white or greenish yellow, globose, with many lustrous seeds. It has been reported as a hallucinogen from Chile and southern Colombia. In Chile, it is known as Taique, in Colombia as borrachero ("intoxicator"). Colombian shamans of the Kamsa' tribe take a tea of the leaves to diagnose disease or "to dream". Some medicine men (Curanderos) assert that they "go crazy" under its influence. Nothing is as yet known of the chemical constituents of Desfontainia." ... "The Indians of Sibundoy use Brugmansia for magico-medicinal purposes, the Mapuche as medicine for recalcitrant children. The Chibcha formerly gave fermented Chicha with Brugmansia seeds to wives and slaves of dead chieftains to induce a stupor before they were buried alive with their husbands or masters. Indians in Peru still believe that Brugmansia permits them to communicate with ancestors and that it can reveal treasures preserved in graves." ... "The drug is usually taken in the form of powdered seeds added to fermented drinks, or as a tea made with the leaves." ... All species of Brugmansia are chemically similar, with scopalomine as their principal psychoactive constituent. Content of lesser alkaloids is also similar. A dangerous hallucinogen, Brugmansia brings on an intoxication often so violent that physical restraint is necessary before the onset of a deep stupor, during which visions are experienced."